ONX-0914 ( PR-957 )
Catalog No: 52013
CAS Number: 960374-59-8
Purity: ≧95.0%
ONX-0914, an inhibitor of the LMP7 and LMP2 subunits of immunoproteasomes, has activity in multiple models of autoimmune diseases.
For research use only. We do not sell to patients.
Chemical Information
| Name | ONX-0914 ( PR-957 ) |
|---|---|
| Iupac Chemical Name | (S)-3-(4-methoxyphenyl)-N-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide |
| Synonyms | ONX 0914 ; ONX0914 ; ONX-0914 ; PR957 ; PR-957 ; PR 957 |
| Molecular Formula | C31H40N4O7 |
| Molecular Weight | 580.67 |
| Smile | N1(CCOCC1)CC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@H](C(=O)[C@@]1(OC1)C)CC1=CC=CC=C1 |
| InChiKey | WQAVPPWWLLVGFK-VTNASVEKSA-N |
| InChi | InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31+/m0/s1 |
| CAS Number | 960374-59-8 |
| Related CAS | 960374-59-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | ≧95.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | LMP7 and LMP2 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
