OATD-02, an orally available dual arginase inhibitor (ARG1 and ARG2), is in phase I clinical development at Molecure for the treatment of patients with advanced and/or metastatic solid tumors, including colorectal cancer, ovarian cancer, pancreatic cancer or renal cell carcinoma.
For research use only. We do not sell to patients.
| Name | OATD-02 |
|---|---|
| Iupac Chemical Name | (1R,2S,5R)-1-amino-5-(2-boronoethyl)-2-((dimethylamino)methyl)cyclohexane-1-carboxylic acid |
| Synonyms | OATD-02 ; OATD 02 ; OATD02 |
| Molecular Formula | C12H25BN2O4 |
| Molecular Weight | 272.15 |
| Smile | O=C([C@]1(N)[C@H](CN(C)C)CC[C@@H](CCB(O)O)C1)O |
| InChiKey | NZNAXQBYXLSQHO-JBLDHEPKSA-N |
| InChi | InChI=1S/C12H25BN2O4/c1-15(2)8-10-4-3-9(5-6-13(18)19)7-12(10,14)11(16)17/h9-10,18-19H,3-8,14H2,1-2H3,(H,16,17)/t9-,10-,12+/m0/s1 |
| CAS Number | 2146132-73-0 |
| Related CAS | 2146132-73-0 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |