Welcome to Sun-shine chemical
+86-27-65522453 sales@sun-shinechem.com

OATD-01

Catalog No.: 208191
Cas No.: 2088453-21-6
Purity : ≧98.0%

OATD-01Bulk in stockcontact us by email for the Bulk quotation.

OATD-01 is a potent dual inhibitor of acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with hAMCase IC50=9nM, hCHIT1 IC50=26nM, m AMCase IC50=8nM, hCHIT1 IC50=29nM.  OATD-01 Significantly Ameliorates Pulmonary Fibrosis in the Bleomycin-Induced Mouse Model. OATD-01 is the first drug candidate targeting members of the chitinase family to enter clinical development.

For research use only. We do not sell to patients.

Chemical Information

NameOATD-01
Iupac Chemical Name5-[4-[(2S,5S)-5-[(4-Chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine
SynonymsOATD-01; OATD 01; OATD01;
Molecular FormulaC19H27ClN6O
Molecular Weight390.91
SmileNC1=NNC(N2CCC(N3C[C@H](C)OC[C@@H]3CC4=CC=C(Cl)C=C4)CC2)=N1
InChiKeySTWVLEKJQQRGMO-GUYCJALGSA-N
InChiInChI=1S/C19H27ClN6O/c1-13-11-26(17(12-27-13)10-14-2-4-15(20)5-3-14)16-6-8-25(9-7-16)19-22-18(21)23-24-19/h2-5,13,16-17H,6-12H2,1H3,(H3,21,22,23,24)/t13-,17-/m0/s1
CAS Number2088453-21-6
Related CAS2088453-21-6

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
TargetsDual Chitinase Inhibitor
MechanismOATD-01 is a potent dual inhibitor of acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with hAMCase IC50=9nM, hCHIT1 IC50=26nM, m AMCase IC50=8nM, hCHIT1 IC50=29nM.
Cell study
Animal study
Clinical study
Not available

Chemical Structure

208191 - OATD-01 | CAS 2088453-21-6

Quick inquiry

Change