Neratinib
Catalog No: 52723
CAS Number: 698387-09-6
Purity: 98%
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | Neratinib |
|---|---|
| Molecular Formula | C30H29ClN6O3 |
| Molecular Weight | 557.04 |
| Smile | CCOc1cc2c(cc1NC(=O)/C=C/CN(C)C)c(c(cn2)C#N)Nc3ccc(c(c3)Cl)OCc4ccccn4 |
| InChiKey | JWNPDZNEKVCWMY-VQHVLOKHSA-N |
| InChi | InChI=1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+ |
| CAS Number | 698387-09-6 |
| MDL | MFCD09752958 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO ��3.6mg/mL Water <1.2mg/mL Ethanol ��1.8mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
