Necrostatin 2 S enantiomer
Catalog No: 6111412
CAS Number: 852391-20-9
Purity: 98%
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.
Necrostatin 2 is a potent in vitro necroptosis inhibitors (exemplified by 1, EC50-0.05 uM) that also were efficacious in an animal model of ischemic stroke. Many Necroptosis inhibitor derivatives are designed for researchers.
Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. It can be induced in a FADD-deficient variant of human Jurkat T cells treated with TNF-a. 5-(1H-Indol-3-ylmethyl)-2-thiohydantoins and 5-(1H-indol-3-ylmethyl)hydantoins were found to be potent necroptosis inhibitors (called necrostatins).
For research use only. We do not sell to patients.
Chemical Information
| Name | Necrostatin 2 S enantiomer |
|---|---|
| Iupac Chemical Name | Necrostatin 2 S enantiomer |
| Synonyms | Necrostatin-2 S enantiomer |
| Molecular Formula | C13H12ClN3O2 |
| Molecular Weight | 277.71 |
| InChiKey | |
| InChi | |
| CAS Number | 852391-20-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
