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NVP-TNKS656

Catalog No: 010408
CAS Number: 1419949-20-4
Purity: 98% 

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2. 

For research use only. We do not sell to patients.

Chemical Information

NameNVP-TNKS656
Iupac Chemical NameN-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide 
SynonymsTNKS656; TNKS-656 
Molecular FormulaC27H34N4O5 
Molecular Weight494.583 
SmileCOC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
InChiKeyDYGBNAYFDZEYBA-UHFFFAOYSA-N
InChiInChI=1S/C27H34N4O5/c1-35-21-6-4-19(5-7-21)26(33)20-8-11-30(12-9-20)16-25(32)31(14-18-2-3-18)15-24-28-23-10-13-36-17-22(23)27(34)29-24/h4-7,18,20H,2-3,8-17H2,1H3,(H,28,29,34)
CAS Number1419949-20-4
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

010408 - NVP-TNKS656 | CAS 1419949-20-4

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