NVP-TAE 226
Catalog No: 52212
CAS Number: 761437-28-9
Purity: 98%
NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2(IC50=3.5 nM); 10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.
For research use only. We do not sell to patients.
Chemical Information
| Name | NVP-TAE 226 |
|---|---|
| Molecular Formula | C23H25ClN6O3 |
| Molecular Weight | 468.94 |
| Smile | CNC(=O)c1ccccc1Nc2c(cnc(n2)Nc3ccc(cc3OC)N4CCOCC4)Cl |
| InChiKey | UYJNQQDJUOUFQJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29) |
| CAS Number | 761437-28-9 |
| MDL | MFCD12031516 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
