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NVP-TAE 226

Catalog No.: 52212
Cas No.: 761437-28-9
Purity : 98% 
52212 - NVP-TAE 226 | CAS 761437-28-9

Catalog number : 52212

CAS number : 761437-28-9

Molecular Formula : C23H25ClN6O3 

Molecular Weight : 468.94 

Chemical Name : NVP-TAE 226

Smile : CNC(=O)c1ccccc1Nc2c(cnc(n2)Nc3ccc(cc3OC)N4CCOCC4)Cl

InChiKey : UYJNQQDJUOUFQJ-UHFFFAOYSA-N

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Molecular FormulaC23H25ClN6O3 
Molecular Weight468.94 
Purity98% 
SmileCNC(=O)c1ccccc1Nc2c(cnc(n2)Nc3ccc(cc3OC)N4CCOCC4)Cl
InChiKeyUYJNQQDJUOUFQJ-UHFFFAOYSA-N
InChiInChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29)
MDLMFCD12031516
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NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2(IC50=3.5 nM); 10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. 

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