NVP-BGJ398
Catalog No: 52743
CAS Number: 872511-34-7
Purity: 98%
NVP-BGJ398(BGJ-398) is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.
For research use only. We do not sell to patients.
Chemical Information
| Name | NVP-BGJ398 |
|---|---|
| Molecular Formula | C26H31Cl2N7O3 |
| Molecular Weight | 560.48 |
| Smile | CCN1CCN(CC1)c2ccc(cc2)Nc3cc(ncn3)NC(=O)N(C)c4c(c(cc(c4Cl)OC)OC)Cl |
| InChiKey | KALOVIRFCJVVNY-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)32-26(36)33(2)25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H2,29,30,31,32,36) |
| CAS Number | 872511-34-7 |
| MDL | MFCD22631499 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO 2 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
