NT-157
Catalog No: 51508
CAS Number: 1384426-12-3
Purity: 98%
NT157 is a small-molecule tyrphostin targeting human IRSes.
For research use only. We do not sell to patients.
Chemical Information
| Name | NT-157 |
|---|---|
| Iupac Chemical Name | (E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide |
| Synonyms | NT157 ; NT 157 |
| Molecular Formula | C16H14BrNO5S |
| Molecular Weight | 412.26 |
| Smile | S=C(NCC1=CC(O)=C(O)C(O)=C1)/C=C/C2=CC(O)=C(O)C(Br)=C2 |
| InChiKey | NIPUPOUEGOSAAO-OWOJBTEDSA-N |
| InChi | InChI=1S/C16H14BrNO5S/c17-10-3-8(4-11(19)15(10)22)1-2-14(24)18-7-9-5-12(20)16(23)13(21)6-9/h1-6,19-23H,7H2,(H,18,24)/b2-1+ |
| CAS Number | 1384426-12-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | yellow solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
References:
1. Krueckl SL et al. Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res. 2004;64:8620.
2. Gleave M, Cox M, Wang YZ: Cell biology of prostate cancer and molecular targets. In Drug Management of Prostate Cancer. (Figg, Chau, Small, Eric, Eds.) Humana Press, Springer New York Dordrecht Heidelberg London, 2010.
3. Reuveni H et al. Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment. Cancer Res 2013;73:4383.
Chemical Structure
