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NPS-1034

Catalog No.: 17030907
Cas No.: 1221713-92-3
Purity : 98% 
17030907 - NPS-1034 | CAS 1221713-92-3

Catalog number : 17030907

CAS number : 1221713-92-3

Molecular Formula : C31H23F2N5O3 

Molecular Weight : 551.54283 

Iupac Chemical Name : N-(3-fluoro-4-((3-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)-2-(4-fluorophenyl)-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxamide 

Smile : FC=1C=C(C=CC1OC1=C2C(=NC=C1)NC=C2C2=CC=CC=C2)NC(=O)C=2C(N(N(C2C)C)C2=CC=C(C=C2)F)=O

InChiKey : RGAZVGZUBCFHRJ-UHFFFAOYSA-N

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SynonymsNPS1034; NPS-1034; NPS 1034 
Molecular FormulaC31H23F2N5O3 
Molecular Weight551.54283 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileFC=1C=C(C=CC1OC1=C2C(=NC=C1)NC=C2C2=CC=CC=C2)NC(=O)C=2C(N(N(C2C)C)C2=CC=C(C=C2)F)=O
InChiKeyRGAZVGZUBCFHRJ-UHFFFAOYSA-N
InChiInChI=1S/C31H23F2N5O3/c1-18-27(31(40)38(37(18)2)22-11-8-20(32)9-12-22)30(39)36-21-10-13-25(24(33)16-21)41-26-14-15-34-29-28(26)23(17-35-29)19-6-4-3-5-7-19/h3-17H,1-2H3,(H,34,35)(H,36,39)
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NPS-1034 is a novel MET inhibitor, which inhibits the activated MET receptor and its constitutively active mutants. NPS-1034, inhibits various constitutively active mutant forms of MET as well as HGF-activated wild-type MET.

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