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Mitapivat

Catalog No: 192191
CAS Number: 1260075-17-9
Purity: >98%

Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.

For research use only. We do not sell to patients.

Chemical Information

NameMitapivat
Iupac Chemical NameN-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide
SynonymsAG348;AG-348;AG 348;PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat.
Molecular FormulaC24H26N4O3S
Molecular Weight450.557
SmileO=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O
InChiKeyXAYGBKHKBBXDAK-UHFFFAOYSA-N
InChiInChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2
CAS Number1260075-17-9
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

192191 - Mitapivat | CAS 1260075-17-9

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