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Miltefosine

Catalog No.: 161009023
Cas No.: 58066-85-6
Purity : 98% by HPLC 
161009023 - Miltefosine | CAS 58066-85-6

Catalog number : 161009023

CAS number : 58066-85-6

Molecular Formula : C21H46NO4P 

Molecular Weight : 407.57 

Iupac Chemical Name : hexadecyl (2-(trimethylammonio)ethyl) phosphate 

Smile : P(=O)(OCCCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)[O-]

InChiKey : PQLXHQMOHUQAKB-UHFFFAOYSA-N

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Synonymsiltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; Miltefosin; Miltefosina; Miltefosinum; Foreign brand name: Miltex ; Abbreviation: HDPC Code name: D18506; 
Molecular FormulaC21H46NO4P 
Molecular Weight407.57 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileP(=O)(OCCCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)[O-]
InChiKeyPQLXHQMOHUQAKB-UHFFFAOYSA-N
InChiInChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
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Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma). Check for active clinical trials or closed clinical trials using this agent. 

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