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Merestinib (LY2801653)

Catalog No.: 178905
Cas No.: 1206799-15-6
Purity : 98.0% 
178905 - Merestinib (LY2801653) | CAS 1206799-15-6

Catalog number : 178905

CAS number : 1206799-15-6

Molecular Formula : C30H22F2N6O3 

Molecular Weight : 552.53 

Iupac Chemical Name : N-(3-fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide 

Smile : FC=1C=C(C=CC1OC=1C=C2C=NN(C2=CC1C=1C=NNC1)C)NC(=O)C=1C(N(C(=CC1)C)C1=CC=C(C=C1)F)=O

InChiKey : QHADVLVFMKEIIP-UHFFFAOYSA-N

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SynonymsLY-2801653;LY 2801653;LY2801653;Merestinib 
Molecular FormulaC30H22F2N6O3 
Molecular Weight552.53 
Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileFC=1C=C(C=CC1OC=1C=C2C=NN(C2=CC1C=1C=NNC1)C)NC(=O)C=1C(N(C(=CC1)C)C1=CC=C(C=C1)F)=O
InChiKeyQHADVLVFMKEIIP-UHFFFAOYSA-N
InChiInChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/h3-16H,1-2H3,(H,33,34)(H,36,39)
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Merestinib, also known as LY2801653, is a n orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. 

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