Welcome to Sun-shine chemical
+86-17702719238 sales@sun-shinechem.com

MS023

Catalog No: 6111012
CAS Number: 1831110-54-3
Purity: 98% 

MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC50 of 4-119 nM.

MS023 potently inhibits PRMT1 (IC50 = 30 9 nM), PRMT3 (IC50 = 119 14 nM), PRMT4 (IC50 = 83 10 nM), PRMT6 (IC50 = 4 0.5 nM), and PRMT8 (IC50 = 5 0.1 nM). Importantly, MS023 does not inhibit any type II PRMTs (PRMT5 and 9) and type III PRMT (PRMT7) at concentrations up to 10 M. MS023 displays high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but is completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. MS023 potently decreases cellular levels of histone arginine asymmetric dimethylation. It also reduces global levels of arginine asymmetric dimethylation and concurrently increased levels of arginine monomethylation and symmetric dimethylation in cells.

 

For research use only. We do not sell to patients.

Chemical Information

NameMS023
Iupac Chemical NameMS023 
SynonymsMS-023; MS 023 
Molecular FormulaC17H25N3O 
Molecular Weight287.4 
InChiKey
InChi
CAS Number1831110-54-3
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111012 - MS023 | CAS 1831110-54-3

Quick Order

Change