MP-A08
Catalog No: 6111524
CAS Number: 219832-49-2
Purity: 98%
MP-A08 is a highly selective ATP competitive SK inhibitor that targets both SK1 and SK2 with Kivalues of 6.9 0.8 M and 27 3 M, respectively.
MP-A08 blocks pro-proliferative signalling pathways, induces mitochondrial-associated apoptosis in a SK-dependent manner, and reduces the growth of human lung adenocarcinoma tumours in a mouse xenograft model by both inducing tumour cell apoptosis and inhibiting tumour angiogenesis. MP-A08 inhibit SK-2, cause a decrease in EC barrier integrity in vitro in both cell type.
MP-A08 suppresses the growth of human lung tumor xenografts in mice.
For research use only. We do not sell to patients.
Chemical Information
| Name | MP-A08 |
|---|---|
| Iupac Chemical Name | MP-A08 |
| Synonyms | MP A08 |
| Molecular Formula | C27H25N3O4S2 |
| Molecular Weight | 519.64 |
| InChiKey | |
| InChi | |
| CAS Number | 219832-49-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
