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MMAE (Monomethyl auristatin E)

Catalog No.: 17022403
Cas No.: 474645-27-7
Purity : 98% 

MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. In International Nonproprietary Names for MMAE-MAB-conjugates, the name vedotin refers to MMAE plus its linking structure to the antibody. MMAE is a potent antimitotic drug derived from peptides occurring in marine shell-less mollusc Dolabella auricularia called dolastatins which show potent activity in preclinical studies, both in vitro and in vivo, against a range of lymphomas, leukemia and solid tumors. MMAE show potency of up to 200 times that of vinblastine, another antimitotic drug used for Hodgkin lymphoma as well as other types of cancer. 

For research use only. We do not sell to patients.

Chemical Information

NameMMAE (Monomethyl auristatin E)
Iupac Chemical NameMMAE (Monomethyl auristatin E) 
SynonymsMMAE; Vedotin; Monomethyl auristatin E 
Molecular FormulaC39H67N5O7 
Molecular Weight717.97858 
CAS Number474645-27-7
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
Formulationoff-white solid 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17022403 - MMAE (Monomethyl auristatin E) | CAS 474645-27-7

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