MLN9708
Catalog No: 52749
CAS Number: 1201902-80-8
Purity: 98%
MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).
For research use only. We do not sell to patients.
Chemical Information
| Name | MLN9708 |
|---|---|
| Molecular Formula | C20H23BCl2N2O9 |
| Molecular Weight | 517.12 |
| Smile | B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)c2cc(ccc2Cl)Cl |
| InChiKey | YTXSYWAKVMZICI-PVCZSOGJSA-N |
| InChi | InChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-17(29)8-20(34-21,19(31)32)7-16(27)28)25-15(26)9-24-18(30)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,30)(H,25,26)(H,27,28)(H,31,32)/t14-,20?/m0/s1 |
| CAS Number | 1201902-80-8 |
| MDL | MFCD18251437 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO 103 mg/mL; Water <1 mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
