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MLN9708

Catalog No: 52749
CAS Number: 1201902-80-8
Purity: 98% 

MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM). 

For research use only. We do not sell to patients.

Chemical Information

NameMLN9708
Molecular FormulaC20H23BCl2N2O9 
Molecular Weight517.12 
SmileB1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)c2cc(ccc2Cl)Cl
InChiKeyYTXSYWAKVMZICI-PVCZSOGJSA-N
InChiInChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-17(29)8-20(34-21,19(31)32)7-16(27)28)25-15(26)9-24-18(30)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,30)(H,25,26)(H,27,28)(H,31,32)/t14-,20?/m0/s1
CAS Number1201902-80-8
MDLMFCD18251437
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Ordering Information

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Purity98% 
SolubilityDMSO 103 mg/mL; Water <1 mg/mL 
Handling
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52749 - MLN9708 | CAS 1201902-80-8

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