ML390
Catalog No: 16122749
CAS Number:
Purity: 98%
ML390 is a human DHODH inhibitor that induces differentiation in acute myeloid leukemia.ML390 was active with an ED50 (effective concentration triggering 50% of its maximal differentiation activity) of 2 M in murine and human AML cell lines, offering insight into the mechanism of overcoming differentiation arrest. DHODH inhibitors demonstrated effective at prolonging survival in animal models of leukemia
For research use only. We do not sell to patients.
Chemical Information
| Name | ML390 |
|---|---|
| Iupac Chemical Name | ML390 |
| Synonyms | N/A |
| Molecular Formula | C21H21F3N2O3 |
| Molecular Weight | 406.4 |
| Smile | C[Si](C)(C)CSCCl |
| InChiKey | IKWIERSJEROYFH-UHFFFAOYSA-N |
| InChi | InChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3 |
| CAS Number | |
| MDL | MFCD17013410 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
