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ML346

Catalog No: 611940
CAS Number: 100872-83-1
Purity: 98% 

ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.

ML346 has good chemical stability, significantly high water solubility, is not reactive with excess glutathione, and is cell permeable. The probe ML346 will help elucidate roles for activation of Hsp70 and HSF-1 in the prevention and progression of cancers, cellular aging, and metabolic and neurodegenerative disorders. ML346 is a novel modulator of proteostasis for protein conformational diseases.


 

For research use only. We do not sell to patients.

Chemical Information

NameML346
Iupac Chemical NameML346 
SynonymsML-346 
Molecular FormulaC14H12N2O4 
Molecular Weight272.26 
InChiKey
InChi
CAS Number100872-83-1
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611940 - ML346 | CAS 100872-83-1

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