ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimulated cAMP production with an IC50 = 2.3 M.
ANTAG3 was selective for TSHR inhibition; half-maximal inhibitory doses were 2.1 M for TSHR and greater than 30 M for LH and FSH receptors .
For research use only. We do not sell to patients.
| Name | ML224 |
|---|---|
| Iupac Chemical Name | ML224 |
| Synonyms | NCGC00242364; ANTAG3; ML-224 |
| Molecular Formula | 1338824-21-7 |
| Molecular Weight | 525.59 |
| InChiKey | |
| InChi | |
| CAS Number | 1338824-21-7 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
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| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |