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ML216

Catalog No: 122101
CAS Number: 1430213-30-1
Purity: 98% 

ML216 is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing similar IC50s of 3.0 and 0.97 M for full length BLM and BLM636C1298 respectively. 

For research use only. We do not sell to patients.

Chemical Information

NameML216
Iupac Chemical Name1-[4-fluoro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea 
SynonymsML 216; ML-216; CID-49852229; CID49852229; CID 49852229 
Molecular FormulaC15H9F4N5OS 
Molecular Weight383.323 
SmileC1=CC(=C(C=C1NC(=O)NC2=NN=C(S2)C3=CC=NC=C3)C(F)(F)F)F
InChiKeyWMCOYUSJXXCHFH-UHFFFAOYSA-N
InChiInChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
CAS Number1430213-30-1
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122101 - ML216 | CAS 1430213-30-1

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