MK-7622 is used as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for the symptomatic treatment of participants with mild to moderate Alzheimer's Disease (AD). Now MK-7622 is in phase II clinical trials by Merck.
For research use only. We do not sell to patients.
| Name | MK7622 |
|---|---|
| Iupac Chemical Name | 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one |
| Synonyms | MK-7622;MK 7622 |
| Molecular Formula | C25H25N3O2 |
| Molecular Weight | 399.48 |
| Smile | O=C1N([C@@H]2[C@@H](O)CCCC2)C=NC3=C1C=C(CC4=CC=C(C)N=C4)C5=CC=CC=C53 |
| InChiKey | JUVQLZBJFOGEEO-GOTSBHOMSA-N |
| InChi | InChI=1S/C25H25N3O2/c1-16-10-11-17(14-26-16)12-18-13-21-24(20-7-3-2-6-19(18)20)27-15-28(25(21)30)22-8-4-5-9-23(22)29/h2-3,6-7,10-11,13-15,22-23,29H,4-5,8-9,12H2,1H3/t22-,23-/m0/s1 |
| CAS Number | 1227923-29-6 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | light-yellow solid to off-white solid |
|---|---|
| Purity | 98% by HPLC |
| Storage | 3 years -20ºCpowder;6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature. |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |