MK-8931 ( Verubecestat )
Catalog No: 1662118
CAS Number: 1286770-55-5
Purity: 98% by HPLC/HNMR
Verubecestat(MK-8931) is a small-molecule inhibitor of beta-secretase cleaving enzyme (BACE)1 and BACE2 in development by Merck for the treatment of Alzheimers Disease.
Verubecestat ( MK-8931 ), Bulk in stock, contact us by email for the Bulk quotation.
For research use only. We do not sell to patients.
Chemical Information
| Name | MK-8931 ( Verubecestat ) |
|---|---|
| Iupac Chemical Name | (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide |
| Synonyms | MK-8931 ; Verubecestat ; MK8931 ; MK 8931 |
| Molecular Formula | C17H17F2N5O3S |
| Molecular Weight | 409.4 |
| Smile | O=C(NC1=CC=C(F)C([C@@](C2)(C)N=C(N)N(C)S2(=O)=O)=C1)C3=NC=C(F)C=C3 |
| InChiKey | YHYKUSGACIYRML-KRWDZBQOSA-N |
| InChi | InChI=1S/C17H17F2N5O3S/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25)/t17-/m0/s1 |
| CAS Number | 1286770-55-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white powder |
|---|---|
| Purity | 98% by HPLC/HNMR |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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