MK-4827
Catalog No: 123007
CAS Number: 1038915-60-4
Purity: 98%
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
For research use only. We do not sell to patients.
Chemical Information
| Name | MK-4827 |
|---|---|
| Iupac Chemical Name | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| Synonyms | Niraparib; MK 4827; MK4827 |
| Molecular Formula | C19H20N4O |
| Molecular Weight | 320.388 |
| Smile | C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
| InChiKey | PCHKPVIQAHNQLW-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24) |
| CAS Number | 1038915-60-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
