MK-4101
Catalog No: 6111008
CAS Number: 935273-79-3
Purity: 98%
MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway
MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway, highly active against Medulloblastoma and Basal Cell Carcinoma. target:SMO In vivo: MK-4101 was highly efficacious against primary medulloblastoma and BCC developing in the cerebellum and skin of Ptch1+/- mice. In vitro: MK-4101 induce deregulation of cell cycle and block of DNA replication in tumors. MK-4101 targets the Hh pathway in tumor cells, showing the maximum inhibitory effect on Gli1. MK-4101 also induce deregulation of cell cycle and block of DNA replication in tumors.
For research use only. We do not sell to patients.
Chemical Information
| Name | MK-4101 |
|---|---|
| Iupac Chemical Name | MK-4101 |
| Synonyms | MK 4101, MK4101 |
| Molecular Formula | C24H24F5N5O |
| Molecular Weight | 493.47 |
| InChiKey | |
| InChi | |
| CAS Number | 935273-79-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
