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MK-0752

Catalog No.: 122949
Cas No.: 471905-41-6
Purity : 98% 
122949 - MK-0752 | CAS 471905-41-6

Catalog number : 122949

CAS number : 471905-41-6

Molecular Formula : C21H21ClF2O4S 

Molecular Weight : 442.904 

Iupac Chemical Name : 3-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]propanoic acid 

Smile : C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

InChiKey : XCGJIFAKUZNNOR-UHFFFAOYSA-N

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SynonymsMK0752; MK 0752 
Molecular FormulaC21H21ClF2O4S 
Molecular Weight442.904 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
InChiKeyXCGJIFAKUZNNOR-UHFFFAOYSA-N
InChiInChI=1S/C21H21ClF2O4S/c22-15-2-5-17(6-3-15)29(27,28)21(18-13-16(23)4-7-19(18)24)11-9-14(10-12-21)1-8-20(25)26/h2-7,13-14H,1,8-12H2,(H,25,26)
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MK-0752 is a moderately potent -secretase inhibitor, which reduces A40 production with IC50 of 5 nM. 

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