MDL 28170
Catalog No: 102610
CAS Number: 88191-84-8
Purity: 98%
MDL 28170 is a potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively), which does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo.
For research use only. We do not sell to patients.
Chemical Information
| Name | MDL 28170 |
|---|---|
| Iupac Chemical Name | N-benzyloxycarbonyl-(S)-valinylphenylalaninal |
| Synonyms | Z-Val-Phe-CHO; Carbobenzoxy-valinyl-phenylalaninal; Calpain Inhibitor III |
| Molecular Formula | C₂₂H₂₆N₂O₄ |
| Molecular Weight | 382.45 |
| Smile | CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2 |
| InChiKey | NGBKFLTYGSREKK-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H26N2O4/c1-16(2)20(24-22(27)28-15-18-11-7-4-8-12-18)21(26)23-19(14-25)13-17-9-5-3-6-10-17/h3-12,14,16,19-20H,13,15H2,1-2H3,(H,23,26)(H,24,27) |
| CAS Number | 88191-84-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
