MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader.
For research use only. We do not sell to patients.
| Name | MDK7526 HCl | 
|---|---|
| Iupac Chemical Name | (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | 
| Synonyms | Protein degrader 1 hydrochloride; MDK7526 HCl; MDK7526; MDK-7526; MDK 7526; VHL Ligand 1; ULM-1. | 
| Molecular Formula | C22H31ClN4O3S | 
| Molecular Weight | 467.025 | 
| Smile | O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl | 
| InChiKey | JYRTWGCWUBURGU-MSSRUXLCSA-N | 
| InChi | InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16(27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28);1H/t16-,17+,19-;/m1./s1 | 
| CAS Number | 1448189-80-7 | 
| Related CAS | 
| Packaging | Price | Availability | Purity | Shipping Time | 
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry | 
| Formulation | off-white solid | 
|---|---|
| Purity | >98% | 
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). | 
| Solubility | Soluble in DMSO | 
| Handling | |
| Shipping Condition | Shipped under ambient temperature | 
| HS Code | 
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | 
