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MDK7526 HCl

Catalog No: 184104
CAS Number: 1448189-80-7
Purity: >98%

MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader.

For research use only. We do not sell to patients.

Chemical Information

NameMDK7526 HCl
Iupac Chemical Name(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Synonyms Protein degrader 1 hydrochloride; MDK7526 HCl; MDK7526; MDK-7526; MDK 7526; VHL Ligand 1; ULM-1.
Molecular FormulaC22H31ClN4O3S
Molecular Weight467.025
SmileO=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
InChiKeyJYRTWGCWUBURGU-MSSRUXLCSA-N
InChiInChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16(27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28);1H/t16-,17+,19-;/m1./s1
CAS Number1448189-80-7
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

184104 - MDK7526 HCl | CAS 1448189-80-7

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