Luminespib ( NVP-AUY922 ; VER-52296 )
Catalog No: 51703
CAS Number: 747412-49-3
Purity: 98%
NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was discovered through a collaboration between The Institute of Cancer Research and the pharmaceutical company Vernalis and licensed to Novartis. It is currently in Phase II clinical trials. NVP-AUY922 is an inhibitor of heat shock protein 90 (Hsp90), which is a chaperone protein that plays a role in the modification of a variety of proteins that have been implicated in oncogenesis. NVP-AUY922 has shown promising activity in preclinical testing against several different tumor types.
Luminespib ( NVP-AUY922 ; VER-52296 ) , Bulk in stock, contact us by email for the Bulk quotation.
For research use only. We do not sell to patients.
Chemical Information
| Name | Luminespib ( NVP-AUY922 ; VER-52296 ) |
|---|---|
| Iupac Chemical Name | 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide |
| Synonyms | Luminespib ; NVP-AUY922 ; VER-52296 |
| Molecular Formula | C26H31N3O5 |
| Molecular Weight | 465.54 |
| Smile | OC1=C(C=C(C(=C1)O)C(C)C)C1=C(C(=NO1)C(=O)NCC)C1=CC=C(C=C1)CN1CCOCC1 |
| InChiKey | NDAZATDQFDPQBD-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32) |
| CAS Number | 747412-49-3 |
| Related CAS | 747412-49-3 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | 2mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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