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Luminespib ( NVP-AUY922 ; VER-52296 )

Catalog No: 51703
CAS Number: 747412-49-3
Purity: 98%

NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was discovered through a collaboration between The Institute of Cancer Research and the pharmaceutical company Vernalis and licensed to Novartis. It is currently in Phase II clinical trials. NVP-AUY922 is an inhibitor of heat shock protein 90 (Hsp90), which is a chaperone protein that plays a role in the modification of a variety of proteins that have been implicated in oncogenesis. NVP-AUY922 has shown promising activity in preclinical testing against several different tumor types.

Luminespib  ( NVP-AUY922 ; VER-52296 ) , Bulk in stock, contact us by email for the Bulk quotation.

For research use only. We do not sell to patients.

Chemical Information

NameLuminespib ( NVP-AUY922 ; VER-52296 )
Iupac Chemical Name5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide 
SynonymsLuminespib ; NVP-AUY922 ; VER-52296
Molecular FormulaC26H31N3O5 
Molecular Weight465.54 
SmileOC1=C(C=C(C(=C1)O)C(C)C)C1=C(C(=NO1)C(=O)NCC)C1=CC=C(C=C1)CN1CCOCC1
InChiKeyNDAZATDQFDPQBD-UHFFFAOYSA-N
InChiInChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
CAS Number747412-49-3
Related CAS747412-49-3

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
Formulationoff-white solid 
Purity98%
Storage3 years -20ºCpowder 
Solubility2mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51703 - Luminespib   (  NVP-AUY922  ;  VER-52296  ) | CAS 747412-49-3

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