Lomitapide free base
Catalog No: 16123035
CAS Number: 182431-12-5
Purity: 98%
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial hypercholesterolemia. Lomitapide is an orally active inhibitor of microsomal triglyceride transfer protein that is indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available for the reduction of LDL-C, total cholesterol, apolipoprotein B, and non-high-density lipoprotein cholesterol in adult patients with HoFH.
For research use only. We do not sell to patients.
Chemical Information
| Name | Lomitapide free base |
|---|---|
| Iupac Chemical Name | Lomitapide free base |
| Synonyms | AEGR 733; AEGR733; AEGR-733; BMS 201038; BMS-201038; BMS201038; BMS 201038-01. Lomitapide mesylate. Brand name: Juxtapid; Lojuxta. |
| Molecular Formula | C39H37F6N3O2 |
| Molecular Weight | 693.73442 |
| Smile | c1ccc(c(c1)c2ccc(cc2)C(F)(F)F)C(=O)NC3CCN(CC3)CCCCC4(c5ccccc5-c6c4cccc6)C(=O)NCC(F)(F)F |
| InChiKey | MBBCVAKAJPKAKM-UHFFFAOYSA-N |
| InChi | InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49) |
| CAS Number | 182431-12-5 |
| MDL | MFCD16620494 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
