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Lifitegrast

Catalog No: 16071412
CAS Number: 1025967-78-5
Purity: 98% by HPLC 

Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses. 

For research use only. We do not sell to patients.

Chemical Information

NameLifitegrast
Iupac Chemical Name(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 
SynonymsSAR-1118; SAR 1118 
Molecular FormulaC29H24Cl2N2O7S 
Molecular Weight615.478 
SmileO1C=CC2=C1C=C(C=C2)C(=O)N2CC1=CC(=C(C(=C1CC2)Cl)C(=O)N[C@H](C(=O)O)CC2=CC(=CC=C2)S(=O)(=O)C)Cl
InChiKeyJFOZKMSJYSPYLN-QHCPKHFHSA-N
InChiInChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1
CAS Number1025967-78-5
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Ordering Information

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FormulationSolid powder 
Purity98% by HPLC 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16071412 - Lifitegrast | CAS 1025967-78-5

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