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LY3023414

Catalog No.: 611808
Cas No.: 1386874-06-1
Purity : 98% 

LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242). 

 

For research use only. We do not sell to patients.

Chemical Information

NameLY3023414
Iupac Chemical Name(S)-8-(5-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(2-methoxypropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one 
SynonymsLY3023414; LY-3023414; LY 3023414. 
Molecular FormulaC23H26N4O3 
Molecular Weight406.48 
SmileOC(C)(C)C=1C=C(C=NC1)C1=CC=2C3=C(C=NC2C=C1)N(C(N3C[C@H](C)OC)=O)C
InChiKeyACCFLVVUVBJNGT-AWEZNQCLSA-N
InChiInChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1
CAS Number1386874-06-1
Related CAS

Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611808 - LY3023414 | CAS 1386874-06-1

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