LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
For research use only. We do not sell to patients.
| Name | LY-3381916 |
|---|---|
| Iupac Chemical Name | (R)-4-fluoro-N-(1-(1-(tetrahydro-2H-pyran-4-carbonyl)indolin-5-yl)ethyl)benzamide |
| Synonyms | LY-3381916;LY3381916;LY 3381916. |
| Molecular Formula | C23H25FN2O3 |
| Molecular Weight | 396.45 |
| Smile | FC1=CC=C(C=C1)C(N[C@@H](C2=CC=C3N(CCC3=C2)C(C4CCOCC4)=O)C)=O |
| InChiKey | NUBWFWVVKLRSHS-OAHLLOKOSA-N |
| InChi | InChI=1S/C23H25FN2O3/c1-15(25-22(27)16-2-5-20(24)6-3-16)18-4-7-21-19(14-18)8-11-26(21)23(28)17-9-12-29-13-10-17/h2-7,14-15,17H,8-13H2,1H3,(H,25,27)/t15-/m1/s1 |
| CAS Number | 2166616-75-5 |
| Related CAS | 2166616-75-5 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |