LXH254 is an orally available inhibitor of all members of the serine/threonine protein kinase Raf family, with potential antineoplastic activity.
For research use only. We do not sell to patients.
| Name | LXH254 free base |
|---|---|
| Iupac Chemical Name | N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide |
| Synonyms | LXH254; LXH-254; LXH 254; |
| Molecular Formula | C25H25F3N4O4 |
| Molecular Weight | 502.4942 |
| Smile | O=C(C1=CC(C(F)(F)F)=NC=C1)NC2=CC=C(C)C(C3=CC(OCCO)=NC(N4CCOCC4)=C3)=C2 |
| InChiKey | UEPXBTCUIIGYCY-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H25F3N4O4/c1-16-2-3-19(30-24(34)17-4-5-29-21(12-17)25(26,27)28)15-20(16)18-13-22(32-6-9-35-10-7-32)31-23(14-18)36-11-8-33/h2-5,12-15,33H,6-11H2,1H3,(H,30,34) |
| CAS Number | 1800398-38-2 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |