Orismilast ( LEO-32731 )
Catalog No: 20625
CAS Number: 1353546-86-7
Purity: ≧98.0%
Orismilast is a phosphodiesterase type 4 (PDE4) inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | Orismilast ( LEO-32731 ) |
|---|---|
| Iupac Chemical Name | 3,5-dichloro-4-(2-(4-(difluoromethoxy)-1',1'-dioxido-2',3',5',6'-tetrahydrospiro[benzo[d][1,3]dioxole-2,4'-thiopyran]-7-yl)-2-oxoethyl)pyridine 1-oxide |
| Synonyms | LEO-32731; LEO 32731; LEO32731; Orismilast; UNII-JH1CX8SG5V; JH1CX8SG5V |
| Molecular Formula | C19H15Cl2F2NO7S |
| Molecular Weight | 510.29 |
| Smile | O=S1(CCC2(CC1)OC3=C(OC(F)F)C=CC(C(CC4=C(Cl)C=[N+]([O-])C=C4Cl)=O)=C3O2)=O |
| InChiKey | ZININGNRPUGNSL-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H15Cl2F2NO7S/c20-12-8-24(26)9-13(21)11(12)7-14(25)10-1-2-15(29-18(22)23)17-16(10)30-19(31-17)3-5-32(27,28)6-4-19/h1-2,8-9,18H,3-7H2 |
| CAS Number | 1353546-86-7 |
| Related CAS | 1353546-86-7 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
