L189
Catalog No: 91001
CAS Number: 64232-83-3
Purity: 98%
L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. L189 will not only provide insights into the cellular function of these enzymes but also serve as lead compounds for the development of anticancer agents.
For research use only. We do not sell to patients.
Chemical Information
| Name | L189 |
|---|---|
| Iupac Chemical Name | (E)-6-amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one |
| Synonyms | L189; L 189; L-189 |
| Molecular Formula | C11H10N4OS |
| Molecular Weight | 246.29 |
| Smile | NC1=C(C(NC(N1)=S)=O)/N=C/C1=CC=CC=C1 |
| InChiKey | SAKOXVNKDMWWLF-AWNIVKPZSA-N |
| InChi | InChI=1S/C11H10N4OS/c12-9-8(10(16)15-11(17)14-9)13-6-7-4-2-1-3-5-7/h1-6H,(H4,12,14,15,16,17)/b13-6+ |
| CAS Number | 64232-83-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
