Ki8751
Catalog No: 17022703
CAS Number: 228559-41-9
Purity: 98%
Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFR and FGFR-2 (IC50 values range from 40 to 170 nM).
For research use only. We do not sell to patients.
Chemical Information
| Name | Ki8751 |
|---|---|
| Iupac Chemical Name | 1-(2,4-difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea |
| Synonyms | N/A |
| Molecular Formula | C24H18F3N3O4 |
| Molecular Weight | 469.41 |
| Smile | FC1=C(C=CC(=C1)F)NC(=O)NC1=C(C=C(C=C1)OC1=CC=NC2=CC(=C(C=C12)OC)OC)F |
| InChiKey | LFKQSJNCVRGFCC-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31) |
| CAS Number | 228559-41-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
