KUS121
Catalog No: 20676
CAS Number: 1357164-52-3
Purity: ≧98.0%
KUS-121 is a small-molecule inhibitor of the transitional endoplasmic reticulum ATPase (valosin-containing protein [VCP]; p97) capable of preventing VCP-regulated ATP depletion and endoplasmic reticulum (ER) stress in VCP-expressing cells, in this way preventing their degeneration.
For research use only. We do not sell to patients.
Chemical Information
| Name | KUS121 |
|---|---|
| Iupac Chemical Name | Sodium 4-amino-3-[(E)-[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]diazenyl]naphthalene-1-sulfonate |
| Synonyms | KUS121 ; KUS 121 ; KUS-121 |
| Molecular Formula | C22H16FN4NaO3S |
| Molecular Weight | 458.44 |
| Smile | CC1=C(C2=CC=C(/N=N/C3=CC(S([O-])(=O)=O)=C(C=CC=C4)C4=C3N)C=N2)C=CC(F)=C1.[Na+] |
| InChiKey | OEEZHMGRDYLKGJ-JGUILPGDSA-M |
| InChi | InChI=1S/C22H17FN4O3S.Na/c1-13-10-14(23)6-8-16(13)19-9-7-15(12-25-19)26-27-20-11-21(31(28,29)30)17-4-2-3-5-18(17)22(20)24;/h2-12H,24H2,1H3,(H,28,29,30);/q;+1/p-1/b27-26+; |
| CAS Number | 1357164-52-3 |
| Related CAS | 1357164-52-3 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
