KRN 633
Catalog No: 51912
CAS Number: 286370-15-8
Purity: 98%
KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-/ and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
For research use only. We do not sell to patients.
Chemical Information
| Name | KRN 633 |
|---|---|
| Iupac Chemical Name | 1-(2-chloro-4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-propylurea |
| Synonyms | N/A |
| Molecular Formula | C20H21ClN4O4 |
| Molecular Weight | 416.86 |
| Smile | ClC1=C(C=CC(=C1)OC1=NC=NC2=CC(=C(C=C12)OC)OC)NC(=O)NCCC |
| InChiKey | VPBYZLCHOKSGRX-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H21ClN4O4/c1-4-7-22-20(26)25-15-6-5-12(8-14(15)21)29-19-13-9-17(27-2)18(28-3)10-16(13)23-11-24-19/h5-6,8-11H,4,7H2,1-3H3,(H2,22,25,26) |
| CAS Number | 286370-15-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | 2mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
