Welcome to Sun-shine chemical
+86-27-65522453 sales@sun-shinechem.com

KRN 633

Catalog No.: 51912
Cas No.: 286370-15-8
Purity : 98% 

KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-/ and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell. 

For research use only. We do not sell to patients.

Chemical Information

NameKRN 633
Iupac Chemical Name1-(2-chloro-4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-propylurea 
SynonymsN/A 
Molecular FormulaC20H21ClN4O4 
Molecular Weight416.86 
SmileClC1=C(C=CC(=C1)OC1=NC=NC2=CC(=C(C=C12)OC)OC)NC(=O)NCCC
InChiKeyVPBYZLCHOKSGRX-UHFFFAOYSA-N
InChiInChI=1S/C20H21ClN4O4/c1-4-7-22-20(26)25-15-6-5-12(8-14(15)21)29-19-13-9-17(27-2)18(28-3)10-16(13)23-11-24-19/h5-6,8-11H,4,7H2,1-3H3,(H2,22,25,26)
CAS Number286370-15-8
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
Formulationwhite solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility2mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51912 - KRN 633 | CAS 286370-15-8

Quick inquiry

Change