KB-0742 is a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers.
For research use only. We do not sell to patients.
| Name | KB-0742 dihydrochloride |
|---|---|
| Iupac Chemical Name | (1S,3S)-N1-(5-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine dihydrochloride |
| Synonyms | KB-0742 ; KB0742 ; KB 0742 2HCl ; KB 0742 dihydrochloride ; KB 0742 hydrochloride ; |
| Molecular Formula | 360.33 |
| Molecular Weight | C16H27Cl2N5 |
| Smile | N[C@@H]1C[C@@H](NC2=CC(C(CC)CC)=NC3=CC=NN23)CC1.[H]Cl.[H]Cl |
| InChiKey | OTUPXOLLHVLWQF-NJHZPMQHSA-N |
| InChi | InChI=1S/C16H25N5.2ClH/c1-3-11(4-2)14-10-16(19-13-6-5-12(17)9-13)21-15(20-14)7-8-18-21;;/h7-8,10-13,19H,3-6,9,17H2,1-2H3;2*1H/t12-,13-;;/m0../s1 |
| CAS Number | 2416874-75-2 |
| Related CAS | 2416874-75-2 (HCl) 2416873-83-9 (free base) |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Yellow solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |