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Ingenol Mebutate

Catalog No: 16123020
CAS Number: 75567-37-2
Purity: 98% 

Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death. Ingenol Mebutate was approved for the topical treatment of actinic keratosis. Ingenol mebutate has also been found to be useful for reactivating latent HIV virus in cells taken from individuals who have tested negative for signs of the disease following extended courses of anti-retroviral drugs, raising the possibility that this drug may be used to expose the last traces of virus, and thus potentially provide a permanent cure for HIV infection. 

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Chemical Information

NameIngenol Mebutate
Iupac Chemical NameIngenol Mebutate 
SynonymsPEP005; PEP-005; PEP 005; ingenol-3-angelate, Ingenol mebutate; trade name Picato 
Molecular FormulaC25H34O6 
Molecular Weight430.53 
SmileC/C=C(/C)\C(=O)O[C@H]1C(=C[C@@]23[C@@]1([C@@H](C(=C[C@@H](C2=O)[C@H]4[C@H](C4(C)C)C[C@H]3C)CO)O)O)C
InChiKeyVDJHFHXMUKFKET-UXMMOKKRSA-N
InChiInChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16-,17-,18+,19-,21+,24+,25+/m1/s1
CAS Number75567-37-2
MDLMFCD07784504
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16123020 - Ingenol Mebutate | CAS 75567-37-2

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