INCB3344
Catalog No: 185215
CAS Number: 1262238-11-8
Purity: >98%
INCB3344是CCR2受体的一种有效的选择性拮抗剂，它在结合拮抗的IC(50)值为5.1 nM (hCCR2)和9.5 nM (mCCR2)和3.8 nM (hCCR2)和7.8 nM (mCCR2)起拮抗趋化作用。
For research use only. We do not sell to patients.
Chemical Information
| Name | INCB3344 |
|---|---|
| Iupac Chemical Name | N-(2-(((3S,4S)-1-(4-(benzo[d][1,3]dioxol-5-yl)-4-hydroxycyclohexyl)-4-ethoxypyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide |
| Synonyms | INCB3344; INCB-3344; INCB 3344. |
| Molecular Formula | C29H34F3N3O6 |
| Molecular Weight | 577.6012 |
| Smile | O=C(NCC(N[C@H]1CN(C2CCC(O)(C3=CC=C(OCO4)C4=C3)CC2)C[C@@H]1OCC)=O)C5=CC=CC(C(F)(F)F)=C5 |
| InChiKey | MZEOSVPWMSEFPW-XYCDVDSTSA-N |
| InChi | InChI=1S/C29H34F3N3O6/c1-2-39-25-16-35(21-8-10-28(38,11-9-21)19-6-7-23-24(13-19)41-17-40-23)15-22(25)34-26(36)14-33-27(37)18-4-3-5-20(12-18)29(30,31)32/h3-7,12-13,21-22,25,38H,2,8-11,14-17H2,1H3,(H,33,37)(H,34,36)/t21?,22-,25-,28?/m0/s1 |
| CAS Number | 1262238-11-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | >98% |
| Storage | 短期可在0-4度保存，数天至数月；长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
