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INCB057643

Catalog No.: 185232
Cas No.: 1820889-23-3
Purity : >98%
185232 - INCB057643 | CAS 1820889-23-3

Catalog number : 185232

CAS number : 1820889-23-3

Molecular Formula : C20H21N3O5S

Molecular Weight : 415.464

Iupac Chemical Name : 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

Smile : CN(C(C(C)(C)O1)=O)C2=C1C(C(C3=C4NC=C3)=CN(C)C4=O)=CC(S(C)(=O)=O)=C2

InChiKey : VZSAMEOETVNDQH-UHFFFAOYSA-N

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SynonymsINCB057643; INCB-057643; INCB 057643;
Molecular FormulaC20H21N3O5S
Molecular Weight415.464
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileCN(C(C(C)(C)O1)=O)C2=C1C(C(C3=C4NC=C3)=CN(C)C4=O)=CC(S(C)(=O)=O)=C2
InChiKeyVZSAMEOETVNDQH-UHFFFAOYSA-N
InChiInChI=1S/C20H21N3O5S/c1-20(2)19(25)23(4)15-9-11(29(5,26)27)8-13(17(15)28-20)14-10-22(3)18(24)16-12(14)6-7-21-16/h6-10,21H,1-5H3
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INCB057643 is a BET inhibitor. INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.

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