IACS-9439
Catalog No: 20911
CAS Number: 2231259-57-5
Purity: 98% Min.
IACS-9439 is a potent, highly selective and orally bioavailable CSF1R inhibitor. IACS-9439 displayed the predicted potency boost, with single-digit nanomolar potency in the MNSF-60 cell phenotypical assay and possessed reasonable metabolic stability when incubated with human and rat microsomal preparations.
For research use only. We do not sell to patients.
Chemical Information
| Name | IACS-9439 |
|---|---|
| Iupac Chemical Name | (1S,2S)-2-(7-chloro-4-methoxy-6-((2-(1-methyl-1H-pyrazol-4- ylamino)pyrimidin-4-yl)methoxy)benzo[d]thiazol-2-ylamino)cyclohexanol |
| Synonyms | IACS-9439 ; IACS9439 ; IACS 9439 |
| Molecular Formula | C23H26ClN7O3S |
| Molecular Weight | 516.02 |
| Smile | ClC1=C(C=C(C=2N=C(SC21)N[C@@H]2[C@H](CCCC2)O)OC)OCC2=NC(=NC=C2)NC=2C=NN(C2)C |
| InChiKey | JYFJGEOXSQLPMB-HOTGVXAUSA-N |
| InChi | InChI=1S/C23H26ClN7O3S/c1-31-11-14(10-26-31)28-22-25-8-7-13(27-22)12-34-17-9-18(33-2)20-21(19(17)24)35-23(30-20)29-15-5-3-4-6-16(15)32/h7-11,15-16,32H,3-6,12H2,1-2H3,(H,29,30)(H,25,27,28)/t15-,16-/m0/s1 |
| CAS Number | 2231259-57-5 |
| Related CAS | 2231259-57-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Light tan foam solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
