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HS-1371

Catalog No.: 192223
Cas No.: 2158197-70-5
Purity : >98%
192223 - HS-1371  | CAS 2158197-70-5

Catalog number : 192223

CAS number : 2158197-70-5

Molecular Formula : C24H24N4O

Molecular Weight : 384.48

Iupac Chemical Name : 7-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-4-(p-tolyloxy)quinoline

Smile : CC1=CC=C(OC2=CC=NC3=CC(C4=CN(C5CCNCC5)N=C4)=CC=C23)C=C1

InChiKey : VPVLPCIBKVWFDT-UHFFFAOYSA-N

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SynonymsHS-1371; HS 1371; HS1371;
Molecular FormulaC24H24N4O
Molecular Weight384.48
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO, not in water
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileCC1=CC=C(OC2=CC=NC3=CC(C4=CN(C5CCNCC5)N=C4)=CC=C23)C=C1
InChiKeyVPVLPCIBKVWFDT-UHFFFAOYSA-N
InChiInChI=1S/C24H24N4O/c1-17-2-5-21(6-3-17)29-24-10-13-26-23-14-18(4-7-22(23)24)19-15-27-28(16-19)20-8-11-25-12-9-20/h2-7,10,13-16,20,25H,8-9,11-12H2,1H3
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HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis. HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner, providing a mechanism of action.

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