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Golvatinib (E7050)

Catalog No.: 52020
Cas No.: 928037-13-2
Purity : 98% 

Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM). Phase 1/2. 

For research use only. We do not sell to patients.

Chemical Information

NameGolvatinib (E7050)
Iupac Chemical Name1,1-Cyclopropanedicarboxamide, N-[2-fluoro-4-[[2-[[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]amino]-4-pyridinyl]oxy]phenyl]-N'-(4-fluorophenyl)- 
SynonymsGolvatinib,E7050 
Molecular FormulaC33H37F2N7O4 
Molecular Weight633.69 
SmileFC1=C(C=CC(=C1)OC1=CC(=NC=C1)NC(=O)N1CCC(CC1)N1CCN(CC1)C)NC(=O)C1(CC1)C(=O)NC1=CC=C(C=C1)F
InChiKeyUQRCJCNVNUFYDX-UHFFFAOYSA-N
InChiInChI=1S/C33H37F2N7O4/c1-40-16-18-41(19-17-40)24-9-14-42(15-10-24)32(45)39-29-21-26(8-13-36-29)46-25-6-7-28(27(35)20-25)38-31(44)33(11-12-33)30(43)37-23-4-2-22(34)3-5-23/h2-8,13,20-21,24H,9-12,14-19H2,1H3,(H,37,43)(H,38,44)(H,36,39,45)
CAS Number928037-13-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52020 - Golvatinib (E7050) | CAS 928037-13-2

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