Giredestrant tartrate
Catalog No.: 20263
Cas No.: 2407529-33-1
Purity : ≧98.0%
Giredestrant tartrate (GDC-9545 tartrate), a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist. Giredestrant tartrate potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain.
For research use only. We do not sell to patients.
Chemical Information
| Name | Giredestrant tartrate |
|---|---|
| Iupac Chemical Name | 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol (2R,3R)-2,3-dihydroxysuccinate |
| Synonyms | Giredestrant tartrate ; GDC-9545 tartrate ; GDC9545 tartrate ; GDC 9545 tartrate ; RG6171 tartrate ; RG-6171 tartrate ; RG 6171 tartrate ; Giredestrant ; |
| Molecular Formula | C31H37F5N4O7 |
| Molecular Weight | 672.64 |
| Smile | C[C@H](C1)N(CC(F)(F)CO)[C@H](C2=C(F)C=C(NC3CN(CCCF)C3)C=C2F)C4=C1C5=C(N4)C=CC=C5.OC([C@H](O)[C@@H](O)C(O)=O)=O |
| InChiKey | QZOTWXMHTSEIJY-WULFPPIKSA-N |
| InChi | InChI=1S/C27H31F5N4O.C4H6O6/c1-16-9-20-19-5-2-3-6-23(19)34-25(20)26(36(16)14-27(31,32)15-37)24-21(29)10-17(11-22(24)30)33-18-12-35(13-18)8-4-7-28;5-1(3(7)8)2(6)4(9)10/h2-3,5-6,10-11,16,18,26,33-34,37H,4,7-9,12-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t16-,26-;1-,2-/m11/s1 |
| CAS Number | 2407529-33-1 |
| Related CAS | 1953133-47-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Yellow-solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
