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Catalog No: 21248
CAS Number: 1953133-47-5
Purity: ≧98.0%

Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.

For research use only. We do not sell to patients.

Chemical Information

Iupac Chemical Name3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol
SynonymsGDC-9545 ; GDC9545 ; GDC 9545 ; RG6171 ; RG-6171 ; RG 6171 ; Giredestrant ;
Molecular FormulaC27H31F5N4O
Molecular Weight522.564
CAS Number1953133-47-5
Related CAS1953133-47-5

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationYellow Solid
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Cell study
Animal study
Clinical study
Not available

Chemical Structure

21248 - Giredestrant | CAS 1953133-47-5

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