+86-27-65522453 sales@sun-shinechem.com

GW4064

Catalog No.: 16071018
Cas No.: 278779-30-9
Purity : 98% by HPLC 
16071018 - GW4064 | CAS 278779-30-9

Catalog number : 16071018

CAS number : 278779-30-9

Molecular Formula : C28H22Cl3NO4 

Molecular Weight : 542.837 

Iupac Chemical Name : 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-benzoic acid 

Smile : ClC1=C(C=CC(=C1)OCC=1C(=NOC1C(C)C)C1=C(C=CC=C1Cl)Cl)C=CC=1C=C(C(=O)O)C=CC1

InChiKey : BYTNEISLBIENSA-UHFFFAOYSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsGW4064; GW-4064 
Molecular FormulaC28H22Cl3NO4 
Molecular Weight542.837 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileClC1=C(C=CC(=C1)OCC=1C(=NOC1C(C)C)C1=C(C=CC=C1Cl)Cl)C=CC=1C=C(C(=O)O)C=CC1
InChiKeyBYTNEISLBIENSA-UHFFFAOYSA-N
InChiInChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)
Coming soon.
GW-4064 is a selective agonist of FXR (EC50 = 15 nM).2 It displays no activity at other nuclear receptors, including the retinoic acid receptor, at concentrations up to 1 M. GW-4064 upregulates adipokine expression in preadipocytes and HepG2 cells. GW4064 could reduce induction of proinflammatory cytokines by LPS in vitro. 

278779-30-9 - Request Bulk Quote

×
278779-30-9 - Request Bulk Quote
Change